Parkinson’s Disease Drugs Cause Heart Damage

Permax is a Parkinson’s Disease drug that is linked in some studies to heart valve damage. Recent studies have linked certain drugs for the treatment of Parkinson ’s disease with valvular heart disease. Pergolide, marketed under the brand name PERMAX by Eli Lilly and Cabergoline marketed under the brand names Dostinex and Cabraser by Pfizer, were found in studies conducted in the Untied Kingdom to produce an increased risk of the development of valvular heart disease in patients receiving these drugs.

Permax in particular was found proven capable of eliciting changes in the heart’s valve leaflets, producing stiffening of the valves and valve regurgitation, which can prove fatal in some patients.

While the drugs are effective for the symptomatic relief of Parkinson’s symptoms, these (ergot-derived dopamine agonists) agents can seriously effect heart valve functionality interfering with what is known as the 5-HT2B receptor, causing patients and their doctors to seriously reconsider the benefits and the risks. If you or a loved one has been taking Permax or Dostinex/Cabraser for the treatment of Parkinson’s disease or the relief of Parkinson’s symptoms has been diagnosed with valvular heart disease you may be entitled to receive legal compensation.



Ashkin Law Firm
Roberta Ashkin, Esq.
300 East 42nd St. 14th Fl
New York New York 10017
Telephone: (646) 779 8520
Facsimile: (212) 593 9997
» click here to locate our office